THE NATIONAL INSTITUTE FOR HEALTH RESEARCH

The NIHR's Health Technology Assessment programme is the largest single national research programme for the NHS. It produces independent research information on the effectiveness, costs and broader impact of healthcare treatments and tests for those who plan, provide or receive care in the NHS. The October-November research grants awards are listed here:

Award winner: Ian Goodyer

Institution: University of Cambridge

Value: £2,406,538

Randomised controlled trial of brief psychodynamic psychotherapy, cognitive behaviour therapy and treatment as usual in adolescents with moderate to severe depression attending routine child and adolescent mental health clinics

Award winner: Ann Netten

Institution: University of Kent at Canterbury

Value: £448,693

Outcomes of social care for adults: developing a preference weighted measure

Award winner: Mark Kilby

Institution: University of Birmingham

Value: £1,024,815

The PLUTO Trial: percutaneous shunting in lower urinary tract obstruction

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Award winner: Aziz Sheikh

Institution: University of Edinburgh

Value: £293,717

Modifying health promotion interventions to meet the needs of ethnic minority groups

Award winner: Sallie Lamb

Institution: University of Warwick

Value: £953,700

Strengthening and stretching for people with rheumatoid arthritis of the hands: the clinical and cost-effectiveness of an exercise programme over and above usual care

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BREAST CANCER CAMPAIGN

The Breast Cancer Campaign funds research to understand how breast cancer develops. Recent grant winners are below and the remainder will be published in due course.

Award winner: Nicola Brown

Institution: University of Sheffield

Value: £113,635

Bevacizumab response in breast cancer: are neuropilins the key?

Award winner: Kairbaan Hodivala-Dilke

Institution: Barts and the London Queen Mary's School of Medicine and Dentistry

Value: £200,577

Understanding the ribosomal protein L29 (RPL29) in breast cancer angiogenesis

Award winner: Anne Ridley

Institution: King's College London

Value: £196,801

Identification of regulators of breast cancer cell invasion and migration

Award winner: Claire Perks

Institution: University of Bristol

Value: £195,795

IGFBP-2, a novel regulator of PTEN: understanding its role in breast cancer

Award winner: Trevor Dale

Institution: Cardiff University

Value: £198,643

Defining the role of Wnt signalling in mammary stem cells

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Award winner: Alan Pockley

Institution: University of Sheffield

Value: £168,616

Hsp70, the breast tumour microenvironment and immunoregulatory T-cells

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Award winner: William Newman

Institution: University of Manchester

Value: £105,977

Pharmacogenetics of aromatase inhibitors in breast cancer

Award winner: John Marshall

Institution: Barts and the London Queen Mary's School of Medicine and Dentistry

Value: £183,7

Effects of integrin (alpha)v(beta)6 expression on HER2-dependent breast cancer cell behaviour

Award winner: Paul Haggarty

Institution: Rowett Research Institute

Value: £146,534

Diet, lifestyle and epigenetics: determinants of breast cancer risk

Award winner: Julia Addington-Hall

Institution: University of Southampton

Value: £209,548

A cohort study of joint pain and stiffness in primary breast cancer

Award winner: Gillian Farnie

Institution: University of Manchester

Value: £459,396

Targeting human breast cancer stem cells to potentiate current DNA damaging therapies

Award winner: Joyce Taylor-Papadimitriou

Institution: King's College London

Value: £14,301

PLU-1/JARID1B and signalling from the ER alpha nuclear receptor.

Award winner: Weiguang Wang

Institution: University of Wolverhampton

Value: £15,000

Targeting Nuclear Factor-kappaB pathway to improve chemotherapy of breast cancer

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Award winner: Elinor Sawyer

Institution: King's College London

Value: £15,000 Molecular characterisation of lobular carcinoma in situ.